To Vaccinate or Not---The Rat Flu Odyssey Continues

[jono]

Yep. Only now it's not only let's not complicate things, a new study suggests the hypothesis there's no point in vaccinating the previously infected is wrong.

Well, it's wrong to say don't vax the recovered, but if:

1) Single dose folks with pre-existing immunity have the highest number of antibodies

That also supports not giving the previously-infected a second dose, right?

[MultiVerse]

^ Yep. It's only one paper but it does suggest a single dose only for seropositve individuals. Previously-infected individuals have a strong reaction to the first vaccine dose whereas the non-infected have a strong reaction to the second dose.

[old goat]

This statement is pure conjecture and a gross generalization.

Who is most likely to be exposed--young, healthy people that gather, don't always wear masks. If they are exposed their risk of getting seriously ill is low. Who is least likely to be exposed--older people who try to isolate themselves, but if they are exposed their risk of getting seriously ill is much higher. It is a generalization of course--as I said earlier, their are plenty of older people still working or living with younger workers, and of course some young people are working from home and not gathering, but hardly conjecture. And in any case--the point of the generalization was that there is no perfect answer as to whom to vaccinate first so base the strategy on getting people vaccinated as quickly as possible rather than on trying to overly manage priority. And in devising such a strategy we need generalizations.

It's a lot like the dilemma of whether to close everything and ruin the economy or open everything and kill people. Sometimes there's no good answers, only less worse.

[DJSapp]

It's the same issue that animal control has dealt with for decades to control feral cats. Is it better to capture males (spreader) and neuter them, or capture females (isolationist) and spay them? You only have so much budget and want to achieve the biggest impact.

The answer I seem to remember was that they went for spaying females, as one tomcat that they didn't capture could still knock up the whole female population. At least by spaying females, they could guarantee some success in bringing numbers down. It's not a perfect world.

[GoldMember]

^^ It's not a perfect world. The best answer is to use whatever means available to get it done as quickly as possible. Simplicity is the best choice if it's the fastest. Also, older people are much more likely to be ready to be vaccinated while younger people who don't see it as a real threat will drag their feet on getting in for their shots.

[Mofro261]

^ Yep. It's only one paper but it does suggest a single dose only for seropositve individuals. Previously-infected individuals have a strong reaction to the first vaccine dose whereas the non-infected have a strong reaction to the second dose.

The very basis of Prime/Boost vaccine strategies.

We still need a little more evidence in the correlates, but it is intriguing to think up to 80-100milllion US might be able to take a rapid serology test when getting the first vaccine that would tell them whether or not they needed to come back for the second booster, and enable us to speed up by several months the approach to immunity at a population level.

[The AD]

We still need a little more evidence in the correlates, but it is intriguing to think up to 80-100milllion US might be able to take a rapid serology test when getting the first vaccine that would tell them whether or not they needed to come back for the second booster, and enable us to speed up by several months the approach to immunity at a population level.

This makes so much sense that I predict it has no chance of actually happening.

[old goat]

The very basis of Prime/Boost vaccine strategies.

We still need a little more evidence in the correlates, but it is intriguing to think up to 80-100milllion US might be able to take a rapid serology test when getting the first vaccine that would tell them whether or not they needed to come back for the second booster, and enable us to speed up by several months the approach to immunity at a population level.

What is different about the J and J and other supposedly single dose vaccines? Are they truly more effective than a single dose of mRNA vaccine or is this more a marketing and distribution strategy. There are very few single dose vaccines. Zoster--but that is for people who have already had varicella. A couple of bacterial vaccines--h flu and pneumococcus. Obviously we don't know how long the protection from the J and J lasts--might not a 2 dose j and j regimen be more effective and last longer? I believe it's being studied.

[GoldMember]

The very basis of Prime/Boost vaccine strategies.

We still need a little more evidence in the correlates, but it is intriguing to think up to 80-100milllion US might be able to take a rapid serology test when getting the first vaccine that would tell them whether or not they needed to come back for the second booster, and enable us to speed up by several months the approach to immunity at a population level.

I like the sound of this but....

This makes so much sense that I predict it has no chance of actually happening.

This is probably the reality, unfortunately.

[KQ]

Dr. Fauci: Here's why you shouldn't wait to get the vaccine

[GoldMember]

Dr. Fauci: Here's why you shouldn't wait to get the vaccine

Yeah, great.... If only we had the vaccines available on a broad basis.

[KQ]

Yeah, great.... If only we had the vaccines available on a broad basis.

W2 seems to be doing well.

We just got issued another 1000 doses. So far W2 has jabbed 6K people (pop. 32K)

[zion zig zag]

Second dose of Moderna is no joke. I feel like I've been hit by a truck this morning.

[Danno]

Apparently, the governor just put "essential workers" like restaurant workers ahead of high risk people with only 1 high risk condition. My wife is fucking pissed.

[seano732]

Second dose of Moderna is no joke. I feel like I've been hit by a truck this morning.

I've been hearing that from a lot of our guys that got the Moderna second dose.....Good news is it seems to last at most 24 hours....Hang in there ZZZ.

[Cono Este]

Watching all the young liberals on my Facebook post pics of their Covid vaccinations, saying just “doing my part” etc
What I want to know is how does a 30 yr old, who works in corporate HR, get a vaccine?

Some selfish a holes out there.


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[Sirshredalot]

Watching all the young liberals on my Facebook post pics of their Covid vaccinations, saying just “doing my part” etc
What I want to know is how does a 30 yr old, who works in corporate HR, get a vaccine?

Some selfish a holes out there.


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I agree: there are certainly some selfish assholes out there.

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[uglymoney]

Apparently, the governor just put "essential workers" like restaurant workers ahead of high risk people with only 1 high risk condition. My wife is fucking pissed.

I feel her. My parents are 75 and 77 and now scrambling to get appointments since they opened it up to all 40,000 65 year olds in the county. Dad has one on the 13th, mom is waitlisted.

My wife is similar with severe asthma and RA. Are they considered pre-conditions? Nobody knows. She still has to go to work though because her engineering services are considered essential to the city. Controlled environment though with almost 100% mask compliance.

I service restaurants and cafeterias. Going in and out of them since and before this all started. Uncontrolled environment and I am at the mercy of managers and employees I have no control over. I hold my breath and zip past people as best I can during my 12 to 14 hour long shifts driving around this godforsaken Trump loving covid infested state.

All the people in the trenches with me already know society doesn't value them. A lot of them don't even value themselves because they spent their lives being beaten down and scoffed at and told they should just find a better job so they matter more. They are happy to let others go first. But for those that do care should society slap us in the face again and push all of us to the back of the line after we spent the last few months keeping the wheels moving and stomachs full while the other half of America worked from home on their computers?

I mean who matters the most? I don't remember anybody thanking me for going to work everyday delivering food. Society just expects the people on the bottom to serve them no matter what.

And if we are racing the British strain do we vaccinate the vulnerable or those with the most potential to spread first?

Maybe 16 year olds should be first. Really.


















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[Name Redacted]

Apparently, the governor just put "essential workers" like restaurant workers ahead of high risk people with only 1 high risk condition. My wife is fucking pissed.

Did ya tell her to get a job at a restaurant? She could practice by making you a sammich!

[Falcon3]

Did ya tell her to get a job at a restaurant? She could practice by making you a sammich!

I think this is the right way to go.

See you in the Tammy Wynette thread in a couple days.

[funkendrenchman]

Apparently, the governor just put "essential workers" like restaurant workers ahead of high risk people with only 1 high risk condition. My wife is fucking pissed.

When did restaurants become essential? They weren't allowed to have in person dining during the original lockdown. Grocery stores, maybe. But have we had issues with food supply due to grocery store workers calling out?

Schools are essential. Can we figure out how to keep kids in school please?

[uglymoney]

When did restaurants become essential? They weren't allowed to stay open during the original lockdown. Grocery stores, maybe. But have we had issues with food supply due to grocery store workers calling out?

Schools are essential. Can we figure out how to keep kids in school please?

Close down delivery, curbside, and drive through windows and get back to me.

But yeah, I already know what you think of me.

[wooley12]

Watching all the young liberals on my Facebook post pics of their Covid vaccinations, saying just “doing my part” etc
What I want to know is how does a 30 yr old, who works in corporate HR, get a vaccine?

Some selfish a holes out there.


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Pics or it didn't happen.

[adrenalated]

Restaurants do not appear to be included in Phase 1B.3, unless you're lumping them under "food and agriculture" which I doubt is the intent of that category.
Edit: this is for Colorado

[Name Redacted]

It changed. Due to the restaurant lobby.
Here’s the article about food workers in the DP:
https://www.denverpost.com/2021/02/0...vaccine-covid/