Speaking of Fat People: The National Association to Advance FAT Acceptance(NAAFA).

[Cisco Kid]

Man, I drink Cokes, eat Twinkies, pie and candy bars all day long and not gain an ounce. That means I'm better than you mags that have to give up the good stuff, work out at the gym and run every day to stay looking respectable. Losers.

[stuckathuntermtn]

Well, kids can do that. Wait till your Cisco 30-something.

If your fat spills into my seat on the plane, fuck you.

[Cisco Kid]

I'm 30 something in my mind, 70 something by the numbers and I weigh 30 lbs more than the 114 I carried as a tight end in JV HS football.

[stuckathuntermtn]

And one day, you'll learn not to ruin the joke

[XXX-er]

Just before the Paul Simon interview CBC did a piece on Ozempic which was very interesting

they interviewed people who had lost > 100 lb who apparently have no concept of being full and just keep eating while ( in a nutshell )the ozempic makes them feel full

Americans were coming across the line to buy up all the Ozempic a few months ago but that got stopped somehow

[I've seen black diamonds!]

I'll just leave this here.......

https://www.wellandgood.com/pace-inclusivity/

[Peruvian]

I'll just leave this here.......

https://www.wellandgood.com/pace-inclusivity/

The Mirnavator is awesome.

[Cisco Kid]

Man, I know just how she feels. I started 4th in a 26 mile XC ski race with a 40lb pack and finished last behind 250 skiers and got in after the scorers had left.

[muted reborn]

She has a good point but I'd imagine it's hard to get volunteers working the course to care too much and everyone needs to get home to start cooking for T-Day or watch a dumb football game.

but the real headline, buried, is -Mila Kunis and Ashton Kutcher’s Favorite Arch Support-Friendly Sneaker Is Already on Sale for the 4th of July

[AK47bp]

but the real headline, buried, is -Mila Kunis and Ashton Kutcher’s Favorite Arch Support-Friendly Sneaker Is Already on Sale for the 4th of July

If they aren’t talking about Sketcher Step-Ins they can fuck right off.

[stuckathuntermtn]

It wasn't about the Lululemon models?

[stuckathuntermtn]

"You ever notice how most people who are against abortion, you wouldn't wanna fuck anyway?"
https://www.bbc.com/news/world-us-canada-65923956

[fomofo]

West Virginia has America's highest obesity rate - more than 40% - and its second highest rate of prescriptions for these obesity drugs.

[Core Shot]

What about the NORTH AMERICAN FREE TEET AGREEMENT

Free the teets!!

[fomofo]

West Virginia has America's highest obesity rate - more than 40% - and its second highest rate of prescriptions for these obesity drugs.

I found it interesting in that piece which aired yesterday no mention was made of using the weight loss drugs to get people out of the clutches of their food addiction, and then focusing on changes to diet and lifestyle to try and keep them moving in the right direction. Just take the shot, use the drug in perpetuity, thus "solving" the problem. An approach I'm sure the pharmaceutical industry would be very happy with. $1,000/month! Nice.

Then today in the news...

Medicare proposes covering weight-loss drugs ... The proposal would expand coverage of anti-obesity drugs to 7.5 million people covered by Medicare and Medicaid, the Biden administration said.

...

The Trump administration is not required to finalize any or all of the proposal. Robert F. Kennedy Jr. — whom Trump has selected to be the next HHS secretary, if confirmed by the Senate — is an avowed critic of weight-loss drugs such as Ozempic, which he has blamed for obfuscating the root causes of poor health in America.

“They’re counting on selling it to Americans because we’re so stupid and so … addicted to drugs,” Kennedy said on Fox News last month.

Kennedy has proposed his own agenda, dubbed “Make America Healthy Again,” that instead emphasizes healthy eating, improved fitness and other federal-led efforts to fight obesity and other chronic diseases.

https://www.washingtonpost.com/healt...ght-loss-drugs

Not sure about a lot of the things that come out of Jr's mouth, but that actually sounds pretty good. We'll see how long it (and he) lasts, and how things shake out over time. (Didn't go so well for Michelle.)

[Trackhead]

^^^GLP-1 agonists aren’t the panache easy weight loss drugs some might think they are. A fair number of folks get pretty sick from them. Discontinuing due to non-life threatening but significant side effects is quite common. About 30% the people using them quit within a year. Then, like so many gastric bypass patients, they slowly turn back to old eating routines and gain weight back.

[bennymac]

^^^GLP-1 agonists aren’t the panache easy weight loss drugs some might think they are. A fair number of folks get pretty sick from them. Discontinuing due to non-life threatening but significant side effects is quite common. About 30% the people using them quit within a year. Then, like so many gastric bypass patients, they slowly turn back to old eating routines and gain weight back.

What about the 70% of people who don’t quit within year 1

[Cisco Kid]

My sister has gotten under 300 with the poke. When her new knee is healed in a year we'll see how it goes. My wife is disappointed with the results so far.

[Trackhead]

What about the 70% of people who don’t quit within year 1

Predicting you might say that, I tried to find data with the best numbers in favor of GLP-1 tolerance. But it turns out, many studies find consistent use much lower, somewhere around 50% depending on drug choice. Is that because of side-effects, or cost?

Discussions around efficacy, side effects, and potential harm are pretty customary in a "shared decision making" approach to healthcare. I'm not sure why that's controversial in a thread specifically related to obesity.

[mtnjam]

^^^GLP-1 agonists aren’t the panache easy weight loss drugs some might think they are. A fair number of folks get pretty sick from them. Discontinuing due to non-life threatening but significant side effects is quite common. About 30% the people using them quit within a year. Then, like so many gastric bypass patients, they slowly turn back to old eating routines and gain weight back.

I see quite a few patients that are taking Ozempic and or metformin are getting quite sick from it. Gastroparesis doesn't sound fun, but hey, lots of scans (here eat some radioactive eggs) can be done to confirm this and keep the healthcare economy going.

[Trackhead]

I'm not against GLP-1s, I've spent countless hours on the phone/computer/writing letters to insurance companies trying to get people approved for them who otherwise don't qualify (not diabetic). It's a huge fucking pain in the ass.

But, it's a simple reality that not everyone tolerates them. Are they better than bariatric surgery? Hell yes. Do some people lose a bunch of weight, yup. Do some people get sick as shit and have repeat ER visits for nausea/vomiting/abd pain, yup, we see that too. And yes, sometimes people get pancreatitis from them too, which is pretty awful.

You'd be nuts to prescribe these meds and not discuss those risk factors with patients.

[Cisco Kid]

Have any studies put %numbers to the risks? Asking for a friend.

My own dose of metformin gives me the shits sometimes.

[Trackhead]

Have any studies put %numbers to the risks? Asking for a friend.

Risks are stratified, nuanced, and I don't think fully understood yet. Link might help, not a study. I've seen a fair number of ED visits for GLP-1 intolerance, but only one case of associated pancreatitis so far. It's pretty uncommon, not sure of specific data in general population.

https://www.uspharmacist.com/article...lp1-initiation

[MagnificentUnicorn]

^^^GLP-1 agonists aren’t the panache easy weight loss drugs some might think they are. A fair number of folks get pretty sick from them. Discontinuing due to non-life threatening but significant side effects is quite common. About 30% the people using them quit within a year. Then, like so many gastric bypass patients, they slowly turn back to old eating routines and gain weight back.

I was talking with one of the gyn surgeons that I work with who happens to be board certified in weight loss medicine. She said that once someone gains and maintains a certain amount of weight that it’s very difficult, sometimes impossible, to get back to a healthy weight with diet and exercise. It changes your metabolism and hormonal function and it’s not going back to healthy levels. These drugs and surgeries are just bandaids for our obesity epidemic, yes it’s a real epidemic. The only sure fire way to be healthy is to not get fat in the first place.


Sent from my iPhone using TGR Forums

[bennymac]

Predicting you might say that, I tried to find data with the best numbers in favor of GLP-1 tolerance. But it turns out, many studies find consistent use much lower, somewhere around 50% depending on drug choice. Is that because of side-effects, or cost?

Discussions around efficacy, side effects, and potential harm are pretty customary in a "shared decision making" approach to healthcare. I'm not sure why that's controversial in a thread specifically related to obesity.

You seem to have adopted a persecuted stance.

Where is the controversy on here you’re speaking of?

Saying “this medication doesn’t help in 100% of cases and also has side effects - some of which can be serious” is the most universal and least controversial statement in medicine.

And why the comment about “you’d be nuts to prescribe these meds without discussing the side effects”? Did someone advocate for that? Is that supposed to be something special/specific about these medications in particular?