I would highly recommend vector format [.eps (Encapsulated PostScript) or .ai (Adobe Illustrator)] files since vector files scale up and down without any loss in quality.
Raster (aka bitmap) format [.bmp (Windows Bitmap), .pcx (Paintbrush), .tiff (Tag Interleave Format), .jpeg (Joint Photographics Expert Group), .gif (Graphics Interchange Format) , .png (Portable Network Graphic), .psd (Adobe PhotoShop)] files do not scale up very well at all especially for the size that you are talking about. You most likely will end up with an extremely unprofessional sign with jagged images/text.
Post a link to the website that you are talking about so that we can see what you are dealing with and provide more specific recommendations. Do you own the website or do you have some existing relationship with the site (partner, etc.)?
For more info Google the words "sign vector vs raster". Here are two links from Googling that explain what I am talking about in more detail with examples.
Raster Images versus Vector Images
http://www.signindustry.com/computer..._v_raster.php3
Converting Raster Images to Vector Images Can Be A Challenge, But It Doesn't Have To Be.
http://www.signindustry.com/computer...ctorImage.php3
I am not a graphic artist but have gone through a similar process where I had to get some large banners similar to what you have mentioned made at Kinkos.
The preferred option would be to request vector .eps or .ai images from the website owner.
The backup option which depending upon on the complexity of the images/text most likely will require hours/$$$ is to convert the raster images to vector images. Adobe Illustrator CS2 has a Live Trace feature that can be used for this process.
Also, talk to the graphics person at the specific Kinkos location that you are printing the banners at to find out exactly which software versions (most likely Adobe Illustrator 10, Adobe Illustrator CS or Adobe Illustrator CS2) are actually loaded on that Kinko's specific computers. I had to have the final Adobe Illustrator CS2 file converted back to Adobe Illustrator 10 for Kinkos to print from it.
Good luck and let us know how this project turns out.
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