Supplements

[Dantheman]

What’s the current evidence for fish oil/omega 3s? I was under the impression that it doesn’t do that much

Just now read this:

https://www.health.harvard.edu/blog/...-2021032422213

“With the availability of today’s data, I would recommend a pure EPA supplement, or one that contains more EPA than DHA.”

2 hr interview with one of the OGs of O3 research. Goes into deep detail about why the big studies have conflicting results.

https://youtu.be/-f-CFQxaUY4

[ntblanks]

Anyone here take B12 for anything? Any negatives?

I'm going to try it, as I have problems with frequent canker sores, and Google says it may help. Can't find much of anything as far as a downside, other than it may do nothing.

take a look at L-Lysine too. Works if you take it early enough.

[ötzi]

2 hr interview with one of the OGs of O3 research:

https://youtu.be/-f-CFQxaUY4

Clifs notes version?

[El Chupacabra]

take a look at L-Lysine too. Works if you take it early enough.

I take lysine every day. Not sure if it does much.

[bobz]

Anyone have specific brands they recommend for Fish Oil, D3 and/or Alanine?

I've read that ingredients and manufacturing practices can matter, depending on the supplement.

I've been taking D3 for a while from the local pharmacy but I have no idea of quality.

I've been taking Nordic Naturals for a while; seems to be well regarded.

[The Reverend Floater]

I've been taking Nordic Naturals for a while; seems to be well regarded.

Gracias.

[LongShortLong]

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I'm on D3, enough to score well on the lab test. In theory you can take too much so it needs to be monitored.
K2, supposed to keep calcium in bones and out of arteries, preventing several problems
Mg, Doc wants me to take it but it goes several hours after food and I eat late, so rarely take it.
B12, I eat mostly plants so this is a critical nutrient I don't get in my diet.

Not much alcohol or sugar or processed food or meat.

I've heard Metformin reduces all-cause mortality for everyone. I'm not on it, but keeping an eye on studies.

Personally I can't tell if any of it works. I think the Mg causes diarrhea if eaten too soon after food.


Somebody asked about brands. Unfortunately supplements are nearly unregulated and there's no guarantee you're getting the amount on the label, or even the ingredient. There's a couple independent labs that do testing, look for their marks.

[skiballs]

Does Dr Pepper and Marlboro reds count as supplements?


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[griffinmyers]

take a look at L-Lysine too. Works if you take it early enough.

Can confirm. Life changer.

I need consistently 500-1000mg per day, and gums are in perfect health. Always struggled with sores before.

If I get lazy and stop, it takes a week for things to start getting bad. Conversely it takes a week or two for things to clear up once I'm back on.

[bagtagley]

Anyone have specific brands they recommend for Fish Oil, D3 and/or Alanine?

I've read that ingredients and manufacturing practices can matter, depending on the supplement.

I switched to this stuff on the recommendation of my internet doctor (Dantheman).

https://a.co/d/8nZzwqO


Consumer Labs is a good resource for supplements. Costs a little money but is worth it to make sure you’re getting decent stuff.

[Grange]

I like the Wild Alaskan Salmon Oil from Trident. 220 mg DHA and 180 mg EPA. I get it at Costco when on sale.

[timackie]

Magnesium Citrate WILL help me recover from big days of exercise

https://www.webmd.com/drugs/2/drug-5...e-oral/details

What kinds of "big days of exercise" does a laxative help you recover from?

[XXX-er]

I've heard Metformin reduces all-cause mortality for everyone. I'm not on it, but keeping an eye on studies..

real MD's prescribe Metformin for type 2 diabetics

[XXX-er]

https://www.webmd.com/drugs/2/drug-5...e-oral/details

What kinds of "big days of exercise" does a laxative help you recover from?

the whole enchilada

for muscle pain and it did work

I very seldom take any supplements

[bennymac]

This is the brand/product that was recommended to me by MD friend

[Kenny Satch]

Anyone here take B12 for anything? Any negatives?

I'm going to try it, as I have problems with frequent canker sores, and Google says it may help. Can't find much of anything as far as a downside, other than it may do nothing.

I take B12 3 times a day for about 4 months now and no issues so far. My minimal meat diet causes me to run low on it.
It's helped eliminate a condition of in my lower legs and feet. Numbness and needle like pain on the bottom of my feet hasn't happened since I got serious about taking it.

[LongShortLong]

real MD's prescribe Metformin for type 2 diabetics

That's where the early studies come from showing the mortality benefit. Diabetics on it were dying less than non-diabetic controls. That's surprising given the stereotype that diabetics are unhealthy fatties. There are and have been some more recent studies, though I haven't tried to understand the results yet. Could be the next (insert name of failed miracle supplement from 80s, 90s, 00s, etc).

[bennymac]

Some people trust one MD for all their health advice and if that MD doesn’t mention it then it can’t be relevant

Which is a really weird expectation to have of one person - especially when you’d probably speak to more people about what truck to buy, where to mount your bindings etc.

And MDs get next to zero training/education on diet or supplements - they’re drowning in chronic disease management and paperwork - leaves little time or energy to look into what might help a fit 40 year old weekend warrior perform better or live longer

[XXX-er]

That's where the early studies come from showing the mortality benefit. Diabetics on it were dying less than non-diabetic controls. That's surprising given the stereotype that diabetics are unhealthy fatties. There are and have been some more recent studies, though I haven't tried to understand the results yet. Could be the next (insert name of failed miracle supplement from 80s, 90s, 00s, etc).

I have been on the cusp of a normal BMI of 24 since I cut diet & sugar so I test high but I'm not fat, but the MD
has been bugging me to get on the Metformin to lower my a1C test readings of 7 ish for a number of years so i was all set to cave in but the latest number was 6.3 which is good so she asked what i did ... drink IPA's

and we skipped it

[Dantheman]

Diabetics on it were dying less than non-diabetic controls. That's surprising...

It's not just surprising, it's completely wild. Berberine is the same thing in supplement non-Rx form. I suspect that either holds little benefit for people who get decent amounts of exercise.

[DarthMarkus]

I don't take it unless I'm doing fairly high intensity stuff, but the combination of L-citrullune, L-arginine, and beet root powder gives me a pretty noticable gain in how far I can push my athletic limits. Does even better when I've been taking creatine monohydrate consistently.

Kinda depends on what your goals are I guess, but vasodilators are an unsung hero IMO.

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[fastfred]

And MDs get next to zero training/education on diet or supplements - they’re drowning in chronic disease management and paperwork - leaves little time or energy to look into what might help a fit 40 year old weekend warrior perform better or live longer

Don't be stupid I see a few different doctors all the time we talk about supplements lifestyle etc but I guess most of my docs are go getters who run ski cycle and are concerned about these things in their personal life

If you are a fat lazy out of shape fuck tard you get back what you are putting in

I put out alot so I get alot back enjoy seeing my long list of Dr's most of then have a thirst for knowing

[LongShortLong]

It's not just surprising, it's completely wild. Berberine is the same thing in supplement non-Rx form. I suspect that either holds little benefit for people who get decent amounts of exercise.

This is a problem I have with most studies. The effect is measured against a population, and there's usually no effort to separate out by known health factors. E.g. say it turns out that compound X reduces heart attack risk by 100%, but only in the 10% of the population that drinks IPAs. Study is done, shows a 10% average benefit across the population - new miracle drug! But it would be much better if we could tease out that there's no benefit unless you also drink those IPAs.

Most posters here aren't like the average population - we get too much exercise. And exercise is the best miracle drug known. The newly discovered miracle drug may provide minimal or no additional benefit, or it may be especially beneficial.

[Kenny Satch]

That's where the early studies come from showing the mortality benefit. Diabetics on it were dying less than non-diabetic controls. That's surprising given the stereotype that diabetics are unhealthy fatties. There are and have been some more recent studies, though I haven't tried to understand the results yet. Could be the next (insert name of failed miracle supplement from 80s, 90s, 00s, etc).

My Dad was put on metformin about a year or 2 before he was diagnosed with prostate cancer. He had a grapefruit size tumour and given 6 months to live. He was lucky he responded well to hormone therapy and that the tumour didn't spread. One naturopath suggested that the metformin stopped the spreading as it suppressed the cancer because as he stated "sugar feeds cancer"
Can't prove a thing as many factors could be why he's still alive but it makes me wonder what if any role it had in his recovery.
He had to get off it some years ago as it was doing harm to his kidneys. He has only 1 barely functioning now.
God willing he'll turn 88 this June.

[mcski]

Metformin is def the new trendy fountain of your math drug among the moneyed class. Price increases coming to a pharmacy near you shortly I’m sure