Plastic-eating enzyme could eliminate billions of tons of landfill waste
https://phys.org/news/2022-04-plasti...-landfill.html
"Researchers at the Cockrell School of Engineering and College of Natural Sciences used a machine learning model to generate novel mutations to a natural enzyme called PETase that allows bacteria to degrade PET plastics. The model predicts which mutations in these enzymes would accomplish the goal of quickly depolymerizing post-consumer waste plastic at low temperatures.
Through this process, which included studying 51 different post-consumer plastic containers, five different polyester fibers and fabrics and water bottles all made from PET, the researchers proved the effectiveness of the enzyme, which they are calling FAST-PETase (functional, active, stable and tolerant PETase).
"This work really demonstrates the power of bringing together different disciplines, from synthetic biology to chemical engineering to artificial intelligence," said Andrew Ellington, professor in the Center for Systems and Synthetic Biology whose team led the development of the machine learning model."
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