Drinking on Fagyl, can it be done?

**smallAXE10** · 12-25-2008, 03:45 PM

So the doc put me on this crazy antibiotic, says I cant drink on it or ill be sorry I did. I laughed and told him that not being able to drink was like Joel Olsteen not being able to inappropriately touch children....er, bad example. Anyway. The pharmacist said the same thing. Now I know you shouldn't drink on AB's but I've never had a problem with it before. In fact. combining pharmecuiticals and alcohol happens to be a hobby of mine. Does anyone have a personal experience or success story with trying to drink on flagyl without dieing?

please share

**Whiteroom_Guardian** · 12-25-2008, 04:05 PM

It just doesn't work very well if at all, so you might as well not take it at all unless you are gonna be sober.

**BUCKYBADGER** · 12-25-2008, 04:15 PM

Haha...drink... i DARE you!

**Fritz** · 12-25-2008, 04:20 PM

Don't do it. Apparently if you have a bad reaction there's a chance of getting violently ill and hospital bound. I don't have any problem drinking on any other kind of meds, but I'm afraid of that one. Flagyl, right?

**crab bait** · 12-25-2008, 04:33 PM

No, you may not drink. The combination will make you horribly sick. Wait for 1 day after you have completed the course of antibiotics.

**Tri-Ungulate** · 12-25-2008, 05:18 PM

Answer is maybe. Flagyl (metronidazole) is supposed to block the aldehyde dehydrogenase (ALDH) enzyme in the liver. This leads to accumulation of acetaldehyde in the blood and makes the person feel sick and queasy - this is how Antabuse (disulfuram) works for people trying to kick their drinking habit.

However, this ALDH effect of metronidazole may not be true after all, based on some more recent studies. Still, I wouldn't recommend it.

**Helicrackjnky** · 12-25-2008, 05:38 PM

Actuallly that drug was used to get some Alcholics off drinking, yes it will make you violently ill & you will need to wait a few days afteryou are done taking it before you drink again. But hey you may be tougher than Chuck Norris so give it a try, let us know how that works out for you.

**XtrPickels** · 12-25-2008, 06:21 PM

Originally Posted by smallAXE10

So the doc put me on this crazy antibiotic, says I cant drink on it or ill be sorry I did. I laughed and told him that not being able to drink was like Joel Olsteen not being able to inappropriately touch children....er, bad example. Anyway. The pharmacist said the same thing. Now I know you shouldn't drink on AB's but I've never had a problem with it before. In fact. combining pharmecuiticals and alcohol happens to be a hobby of mine. Does anyone have a personal experience or success story with trying to drink on flagyl without dieing?

please share

it sounds like you deserve to try it.
Bring a camera and report back later.

advres · 12-25-2008, 08:19 PM

Do it and post a TR.

EDIT - seems I should read the thread first...xtrpickels beat me to it.

**Jim S** · 12-25-2008, 08:30 PM

**brannen** · 12-25-2008, 08:34 PM

this is how Antabuse (disulfuram) works for people who are legally forced to kick their drinking habit.

fixed it for you

**pharmer** · 12-25-2008, 10:19 PM

you can drink, but I doubt it will result in the desired effects that you are seeking in normal alcohol consumption. either don't take the antibiotic or drink and get sick... in my experience, its not worth the risk

**Duffman** · 12-25-2008, 11:03 PM

^^^^^ see above.

This isnt a "oh cool, I shouldn't mix percs and booze, he he" type of warning, its a you will probably get a splitting headache and projectile vomit type of reaction.

So obviously, do it and video TR to follow

And BTW, I've never heard of "Fagyl", but it is probably something they slip into your drink at the turkish bathhouse, not that there is anything wrong with that. The antibiotic is usually known as Flagyl.

advres · 12-25-2008, 11:13 PM

Originally Posted by brannen

fixed it for you

brannen for the win!

**srsosbso** · 12-26-2008, 09:13 AM

tri-ungulate is correct. You won't simply fail to get drunk, you will very likely feel like shit if you drink.

**tommyvee** · 12-26-2008, 10:58 AM

If you ask for medical/drug use advice on TGR, you probably deserve what you get.
But my experience taking Flagyl for giardia was that Flagyl gave me a solid hangover, without drinking anything.
From wikipedia,..
High doses and/or long-term systemic treatment with metronidazole is associated with the development of black hairy tongue, leukopenia, neutropenia, increased risk of peripheral neuropathy and/or CNS toxicity.[2]

Metronidazole is listed by the International Agency for Research on Cancer (IARC) as a potential human carcinogen. Although some of the testing methods have been questioned, it has been shown to cause cancer in experimental animals.[5] Nevertheless, it appears to have a fairly low potential for cancer risk and under most circumstances the benefits of treatment outweigh the risk.

Consuming ethanol (alcohol) while using metronidazole causes a disulfiram-like reaction with effects that can include nausea, vomiting, flushing of the skin, tachycardia (accelerated heart rate), and shortness of breath.[6] Consumption of alcohol should be avoided by patients during systemic metronidazole therapy and for at least 48 hours after completion of treatment.[2] However, the mechanism of this reaction in the clinical setting has recently been questioned by some authors,[7][8] and a possible central toxic serotonin reaction for the alcohol intolerance suggested.[9]

So if you want to go for the central toxic serotonin reaction, flagyl and alcohol will probably get you there, if that's where you want to go..

**powhore** · 12-26-2008, 11:02 AM

Originally Posted by tommyvee

High doses and/or long-term systemic treatment with metronidazole is associated with the development of black hairy tongue, leukopenia, neutropenia, increased risk of peripheral neuropathy and/or CNS toxicity.[2]

Metronidazole is listed by the International Agency for Research on Cancer (IARC) as a potential human carcinogen. Although some of the testing methods have been questioned, it has been shown to cause cancer in experimental animals.[5] Nevertheless, it appears to have a fairly low potential for cancer risk and under most circumstances the benefits of treatment outweigh the risk.

Dude, Alcohol causes more cancers and adverse effects than metronidazole ever could.

**powhore** · 12-26-2008, 11:08 AM

I worked on an Indian reservation for a spell. Many of the native american alcoholics could tolerate the effects. Hard core drinkers will have less of a reaction. If you are a lightweight, you'll get tossed.
It also depends on your dose. The generic 500mg 3X daily dosage is tolerable (but still not advisable) for chronic drinkers.

Any TR yet, bigAXE10?

**jepilot** · 12-26-2008, 11:56 AM

Disulfuram reactions are not fun. Metronidazole is a chemical like the one they used to give Alcoholics in order to break the habit (they would associate drinking with puking). It's bad news, man. I wouldn't do it, but I hate puking...

EDIT: Looks like Tri-Ungulate beat me to it.

**smallAXE10** · 12-26-2008, 04:11 PM

alright. Its currently 5:00 pm. Ive been drinking steadily since 12:00. no advcerse effects yet. and i I just noticed that i misspelled flagyl. im sorry. Im doing well so far actually. happy hour is rapidly approaching and Im preparing for battle. The camera is is on hand in the event that something should go awry and in any case, A tr will be made tomorow. This is purley an experiment and Im making this sacrafice for the best interest of mty fellow maggots.....and the fact that Im sick and I need to take this outdated crappy drug,.....and im an alcoholic.

gfame on!

**axebiker** · 12-26-2008, 04:23 PM

Can't believe it hasn't been said yet... PADDED ROOM, JONG.

knarshedmotatoes · 12-26-2008, 06:24 PM

from wikipedia on taking it with alchohol

Consuming ethanol (alcohol) while using metronidazole causes a disulfiram-like reaction with effects that can include nausea, vomiting, flushing of the skin, tachycardia (accelerated heart rate), and shortness of breath. Consumption of alcohol should be avoided by patients during systemic metronidazole therapy and for at least 48 hours after completion of treatment. However, the mechanism of this reaction in the clinical setting has recently been questioned by some authors, and a possible central toxic serotonin reaction for the alcohol intolerance suggested.

you gonna have fun tonight

**GiBo** · 05-04-2018, 02:20 PM

LOL TGR. I just got prescribed this shit and the pharmacist said no alcohol. I google 'metronidazole and alochol' and this thread is the 7th result. Strong work.

It's just the shits and cramps. I think I'll wait for the lab results before taking these. I can skip the booze a little, but they want 10 fucking days. That's through two beautiful, sunny weekends. Fuck that shit.