Originally Posted by
Mofro261
Unless some of those 5-11 yro's have already gone through puberty... risk of myocarditis should be very low to extremely low, and even lower in girls.
Turns out the hormone Testosterone will also influence the immune response, or in some cases the magnitude of that response, by upregulating a pro-inflammatory cytokine (IL1-β) that is also induced as part of the innate response to either viral infection or mRNA vaccination via recognition of those same TLR, RLR, and NOD innate signaling sensors in cytoplasmic and endosomal compartments. IL1-β is involved in cardiac remodeling and recruitment of tcells, macrophages to heart tissues with resulting inflammation.
Chances are still 6-10X higher for myocarditis from actual viral infection with Sars2 vs an mRNA vaccine in boys 15-17 which have the highest rates vs all other age/sex.
(Of course, consult your dr.)