Fascinating research on non nutritive sweeteners (wish they’d done xylitol) and their effects on mouth and gut microbiome, insulin secretion, etc.
https://www.cell.com/cell/fulltext/S...674(22)00919-9
Their reported highlights (though there’s more in the Discussion section):
-Randomized-controlled trial on the effects of non-nutritive sweeteners in humans
-Sucralose and saccharin supplementation impairs glycemic response in healthy adults
-Personalized effects of non-nutritive sweeteners on microbiome and metabolome
-Impacts on the microbiome are causally linked to elevated glycemic response