the researchers found that “the anabolic response to protein ingestion has no apparent upper limit in magnitude and duration in vivo in humans.” The 100-gram protein condition resulted in more amino acid availability and muscle protein synthesis, around 30% higher over 12 hours than the 25-gram test. The methodological key was a 12-hour sampling window that allowed researchers to see longer-term responses. While the anabolic responses were elevated in the first 4 hours (around 20%), the most significant elevation was in hours 4-12 (around 40%). As the authors said:
Quote:
“These data support our hypothesis that even very large amounts of dietary protein are effectively utilized to support postprandial tissue anabolism but require a more prolonged period for complete protein digestion and amino acid absorption to become available for incorporation into tissues.”
